Knowledge How does the SHR procedure affect hair stem cells? Discover the Science Behind Pain-Free Permanent Hair Removal
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Tech Team · Belislaser

Updated 2 days ago

How does the SHR procedure affect hair stem cells? Discover the Science Behind Pain-Free Permanent Hair Removal


The Super Hair Removal (SHR) procedure targets the biological life-support system of the hair follicle rather than simply burning the hair shaft. By continuously heating the skin, the procedure raises the temperature of the hair's stem cells to approximately 45 degrees Celsius. This specific thermal level denatures the proteins within the stem cells, effectively severing the nutrient supply line to the hair root.

By focusing on protein denaturation within the stem cells, SHR disables the follicle's ability to feed the hair root. This "starvation" method causes the hair to detach and fall out over time, rather than being instantly vaporized.

The Science of Protein Denaturation

Targeting the Nutrient Source

The primary target of the SHR procedure is the stem cell cluster responsible for sustaining the hair.

These cells act as the nutrient providers for the hair root. Without their active function, the hair follicle cannot maintain its structural integrity or growth cycle.

The 45-Degree Threshold

The procedure relies on a precise thermal window.

The skin is heated until the stem cells reach 45 degrees Celsius. This temperature is critical because it is the point at which specific cellular proteins begin to denature (lose their structure and function).

The Starvation Effect

Once the proteins are denatured, the stem cells cease to function.

Consequently, the nutrient supply to the hair root is cut off. Deprived of support, the hair follicle degrades, and the existing hair eventually precipitates (falls out) naturally.

How SHR Differs from Traditional Methods

Gradual Heating vs. High-Energy Spikes

Traditional laser hair removal often uses a single, high-energy pulse to destroy the follicle.

In contrast, SHR employs a method of gradual heating. It delivers low-fluence energy at a high frequency (multiple smaller pulses). This accumulates heat in the dermis until the target temperature is reached, rather than shocking the tissue with a single blast.

Pain Reduction and Safety

Because the energy is distributed gradually, the procedure is often described as virtually pain-free.

Most patients report only a mild warming sensation. Additionally, built-in cooling technology further protects the surrounding healthy tissue, significantly reducing the risk of burns, redness, or blisters.

Understanding the Trade-offs

The Melanin Dependency

While SHR targets stem cells, it still requires a pathway to reach them.

The laser targets melanin (pigment) in the hair to guide the heat to the follicle. Therefore, the treatment is most effective on dark, coarse hair.

Limitations on Light Hair

Physics dictates the limitations of this technology.

Individuals with light blonde, grey, or red hair lack sufficient pigment to absorb the laser energy effectively. For these users, it is difficult for the heat to penetrate and damage the stem cells, making the treatment largely ineffective.

Making the Right Choice for Your Goals

To determine if SHR is the correct mechanism for your needs, consider the following biological factors:

  • If your primary focus is comfort and safety: SHR is ideal because the gradual heating method minimizes pain and drastically reduces the risk of burns compared to single-pulse lasers.
  • If your primary focus is treating darker skin tones: SHR is highly recommended as the low-fluence pulses target the follicle precisely without damaging or discoloring the surrounding pigment-rich skin.
  • If your primary focus is treating light or grey hair: You should likely seek alternative methods (such as electrolysis), as SHR relies on melanin to transport heat to the stem cells.

By denaturing stem cell proteins to cut off nutrients, SHR offers a sophisticated, low-impact route to permanent hair reduction.

Summary Table:

Feature SHR Technology Traditional Laser
Biological Target Hair Stem Cells (Protein Denaturation) Hair Root (Melanin Blast)
Temperature Threshold Precise 45°C (Gradual Heating) High Temperature Spikes
Pain Level Virtually Painless (Warming Sensation) Moderate to High (Snapping Sensation)
Safety Mechanism Low Fluence + High-Frequency Pulses Single High-Energy Pulse
Best For All Skin Tones, Dark Coarse Hair Fair Skin with Dark Hair

Elevate Your Clinic with Professional-Grade SHR Solutions

Are you looking to provide your clients with the ultimate pain-free hair removal experience? BELIS specializes in professional-grade medical aesthetic equipment designed exclusively for clinics and premium salons.

Our advanced Diode Laser and SHR systems utilize precise thermal targeting to denature stem cells safely, ensuring superior results across diverse skin tones. Beyond hair removal, our portfolio includes CO2 Fractional and Nd:YAG lasers, HIFU, Microneedle RF, EMSlim body sculpting, and Hydrafacial systems.

Partner with BELIS to bring industry-leading technology and exceptional value to your business. Contact us today to request a quote or consultation and see how our specialized devices can transform your service offerings.

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