Knowledge What is the mechanism of action when combining CO2 Fractional Laser with CO2 gas subcision for deep acne scars?
Author avatar

Tech Team · Belislaser

Updated 2 days ago

What is the mechanism of action when combining CO2 Fractional Laser with CO2 gas subcision for deep acne scars?


The combination mechanism relies on the simultaneous use of thermal ablation and pneumatic physical separation to treat the full depth of the scar. The Carbon Dioxide (CO2) Fractional Laser delivers thermal energy to reconstruct tissue structures at depths up to 4mm, while injected CO2 gas uses high mechanical pressure to physically sever the fibrous bands tethering the scar to deeper layers.

By integrating thermal remodeling with mechanical release, this dual approach addresses the root causes of deep scarring: the laser repairs the dermal structure from the surface, while the gas releases tension and stimulates blood flow from underneath.

The Mechanism of Pneumatic Subcision (CO2 Gas)

Mechanical Severing of Fibrous Bands

Deep acne scars are often held in a depressed position by rigid fibrous bands pulling the skin downward.

In this protocol, CO2 gas is injected subcutaneously using high-pressure needles. The force of the gas acts as a "pneumatic scalpel," utilizing mechanical pressure to physically sever these fibrous tethers (subcision), allowing the skin to elevate.

Oxygenation and Neovascularization

Beyond the physical release, the presence of the gas induces a biological response in the tissue bed.

The injected CO2 increases local oxygen content within the tissue. This stimulates the formation of new blood vessels (angiogenesis), which creates a nutrient-rich environment that supports faster healing and more robust collagen synthesis.

The Mechanism of Fractional CO2 Laser

Creation of Micro-Ablative Zones

While the gas works subcutaneously, the laser targets the epidermis and dermis through Microscopic Treatment Zones (MTZs).

The laser vaporizes damaged tissue in precise columns, known as ablation columns, reaching depths of up to 4mm. These microscopic injuries trigger the body's wound-healing response to remove damaged scar tissue physically.

Thermal Stimulation and Remodeling

Surrounding the ablated columns, the laser generates deep thermal zones that stimulate fibroblasts.

This heat shock triggers the production of new collagen and elastic fibers (neocollagenesis). Because the laser operates fractionally—leaving "islands" of healthy, untreated tissue between the columns—the skin heals rapidly, utilizing the healthy cells to assist in epidermal remodeling.

Synergistic Effects on Tissue

Comprehensive Collagen Reorganization

The combined protocol attacks the scar structure from two distinct angles.

The laser induces collagen contraction and tightening in the upper layers via heat. Simultaneously, the subcision triggers collagen reorganization in the deep dermal layer via mechanical trauma and increased oxygenation.

Enhanced Healing Environment

The synergy of these two methods creates an optimal environment for tissue regeneration.

The laser removes the old, damaged surface texture. The gas subcision ensures the new tissue is not pulled back down by tethers, while the increased blood flow ensures the metabolically active fibroblasts have the oxygen required to build new structure.

Understanding the Trade-offs

Controlled Trauma is Necessary

To achieve these results, the skin must undergo significant controlled injury.

The creation of ablative zones and the physical tearing of fibrous bands triggers inflammation. This is the catalyst for healing, but it means the treatment is not "no-downtime"; the body requires energy and time to resolve the thermal and mechanical injury.

Depth vs. Recovery

Deeper treatment yields better results for deep scars but extends the recovery window.

While the fractional pattern significantly shortens healing compared to fully ablative lasers, reaching a depth of 4mm is aggressive. Patients must balance the need for deep structural correction with the reality of the re-epithelialization timeline.

Making the Right Choice for Your Goal

This combination therapy is a potent tool for structural skin revision. Here is how to assess if it aligns with your objectives:

  • If your primary focus is releasing deep, tethered rolling or boxcar scars: The pneumatic subcision component is essential to physically break the bands that laser alone cannot reach.
  • If your primary focus is surface texture and pore size reduction: The fractional laser component will drive the necessary epidermal turnover and collagen tightening.
  • If your primary focus is minimizing total recovery time: Be aware that combining deep mechanical subcision with 4mm laser ablation creates a compound recovery period that requires strict post-procedure care.

The most effective treatment plans respect the biology of the scar, treating the deep tethering first and the surface texture second to ensure long-term smoothness.

Summary Table:

Mechanism Component Action Type Primary Function Treatment Depth
CO2 Fractional Laser Thermal Ablation Creates MTZs, stimulates collagen & resurfaces Up to 4mm
CO2 Gas Subcision Mechanical Pressure Severs fibrous tethers (pneumatic scalpel) Subcutaneous
Synergistic Effect Biological Response Enhances oxygenation & neovascularization Full Skin Depth

Elevate Your Clinic’s Scar Treatment Results with BELIS

Are you looking to provide your patients with the ultimate solution for deep structural skin revision? BELIS specializes in professional-grade medical aesthetic equipment designed exclusively for clinics and premium salons. Our advanced CO2 Fractional Laser systems and specialized care devices provide the precision and power needed for high-impact protocols like combined laser-subcision therapy.

By partnering with BELIS, your clinic gains access to:

  • Advanced Laser Systems: High-performance CO2 Fractional, Nd:YAG, and Pico lasers.
  • Comprehensive Solutions: From body sculpting (EMSlim, Cryolipolysis) to skin health (Hydrafacial, Skin Testers).
  • Unmatched Value: Superior technology that ensures faster healing, robust collagen synthesis, and higher patient satisfaction.

Ready to upgrade your treatment offerings?
Contact us today to discuss your equipment needs!

References

  1. The efficacy and safety of combination therapy using deep penetrated CO2 fractional laser and subcision with CO2 gas for acne scar. DOI: 10.1016/j.jaad.2016.02.1121

This article is also based on technical information from Belislaser Knowledge Base .

Related Products

People Also Ask

Related Products

Fractional CO2 Laser Machine for Skin Treatment

Fractional CO2 Laser Machine for Skin Treatment

CO2 Fractional Laser Machine for skin resurfacing, scar removal & anti-aging. 40W/60W power, adjustable modes & minimal downtime. FDA-approved for safe treatments.

Fractional CO2 Laser Machine for Skin Treatment

Fractional CO2 Laser Machine for Skin Treatment

CO2 Fractional Laser Machine for skin rejuvenation, scar removal, and gynecological treatments. Dual-mode precision with customizable settings. Learn more now!

Pico Picosecond Laser Machine for Tattoo Removal Picosure Pico Laser

Pico Picosecond Laser Machine for Tattoo Removal Picosure Pico Laser

Pico laser machine for tattoo removal, pigmentation, and skin rejuvenation. Safe for all skin types, minimal downtime. Learn more now!

Hydrafacial Machine Facial Clean Face and Skin Care Machine

Hydrafacial Machine Facial Clean Face and Skin Care Machine

Professional Hydrafacial machine for deep cleansing, exfoliation, and hydration. Advanced 6-in-1 technology with RF lifting and silent operation. Ideal for spas and clinics.

Pico Laser Tattoo Removal Machine Picosure Picosecond Laser Machine

Pico Laser Tattoo Removal Machine Picosure Picosecond Laser Machine

Picosecond laser machine for tattoo removal & skin rejuvenation. Triple-wavelength, high-energy pulses for faster results with minimal downtime. Safe for all skin types.

Hydrofacial Machine with Facial Skin Analyzer and Skin Tester

Hydrofacial Machine with Facial Skin Analyzer and Skin Tester

Advanced facial skin analyzer with AI diagnostics, hydrofacial treatment, and multi-spectral imaging for professional skincare. Customizable RF, ultrasound, and ion therapy.

Cryolipolysis Fat Freezing Machine and Ultrasonic Cavitation Device

Cryolipolysis Fat Freezing Machine and Ultrasonic Cavitation Device

Advanced body contouring system with cryolipolysis, RF, and laser for fat reduction and skin tightening. Non-invasive, FDA-cleared, visible results.

Ultrasonic Cavitation Radiofrecuency Machine for Body Slimming

Ultrasonic Cavitation Radiofrecuency Machine for Body Slimming

BELIS Ultrasonic Cavitation Machine for non-invasive fat reduction, skin tightening, and body contouring. Professional-grade RF technology for clinics.

4D 12D HIFU Machine Device for Skin Tightening

4D 12D HIFU Machine Device for Skin Tightening

Non-invasive HIFU device for skin tightening & fat reduction. 8 cartridges, 20,000 shots, 0.2J-3.0J energy. Painless, no downtime.

Cryolipolysis Fat Freezing Machine Ultrasonic Cavitation Fat Reducing Device

Cryolipolysis Fat Freezing Machine Ultrasonic Cavitation Fat Reducing Device

Advanced fat reduction system for non-invasive body sculpting, skin tightening, and cellulite treatment. FDA-cleared, multi-technology integration.

Cryolipolysis Fat Freezing Cavitation Lipo Laser Machine

Cryolipolysis Fat Freezing Cavitation Lipo Laser Machine

Non-invasive Cryolipolysis-Cavitation-Lipo Laser machine for fat reduction, body contouring, and skin tightening. Ideal for clinics and spas.

12D HIFU Machine Device for Facial HIFU Treatment

12D HIFU Machine Device for Facial HIFU Treatment

12D HIFU machine for non-invasive skin tightening & body contouring. Reduces wrinkles, lifts sagging skin, targets fat. Safe, no downtime. 2-year warranty.

Clinic Diode Laser Hair Removal Machine with SHR and Trilaser Technology

Clinic Diode Laser Hair Removal Machine with SHR and Trilaser Technology

Discover the Diode Hair Removal Laser: Advanced, pain-free, and versatile for all skin tones. Achieve permanent results with cutting-edge technology.

Trilaser Diode Hair Removal Machine for Beauty Clinic Use

Trilaser Diode Hair Removal Machine for Beauty Clinic Use

Discover the Trilaser Diode Hair Removal Machine for effective, pain-free hair removal on all skin types. Explore advanced features and benefits now!

Multifunctional Laser Hair Growth Machine Device for Hair Growth

Multifunctional Laser Hair Growth Machine Device for Hair Growth

BELIS Laser Hair Growth Machine: 650nm cold laser therapy for hair regrowth, safe & effective for clinics. Non-invasive, FDA-approved, visible results.

Cryolipolysis Fat Freezing Machine Cavitation Lipo Laser Machine

Cryolipolysis Fat Freezing Machine Cavitation Lipo Laser Machine

360 Degree Cryolipolysis with 40K Cavitation, Multipolar Radiofrecuency for Face and Body, with Lipo Laser for non-surgical fat reduction, body slimming, and skin tigtening, skin rejuvenation, clinic-grade results.

Cryolipolysis Fat Freezing Machine with Cavitation and Laser Lipolysis

Cryolipolysis Fat Freezing Machine with Cavitation and Laser Lipolysis

Advanced body contouring system with cryolipolysis, RF, cavitation & laser for non-surgical fat reduction and skin tightening.

Diode Tri Laser Hair Removal Machine for Clinic Use

Diode Tri Laser Hair Removal Machine for Clinic Use

Diode Laser Hair Removal Machine: Safe, effective, and pain-free for all skin types. Achieve permanent results with advanced multi-laser technology.

Vaginal Tighten HIFU Gynecology HIFU Treatment

Vaginal Tighten HIFU Gynecology HIFU Treatment

Noninvasive Vaginal HIFU for tightening, rejuvenation & enhanced wellness. Safe, pain-free treatments with lasting results. Learn more!

Diode Laser SHR Trilaser Hair Removal Machine for Clinic Use

Diode Laser SHR Trilaser Hair Removal Machine for Clinic Use

Discover the diode laser hair removal machine for painless, effective treatments on all skin types. Safe, versatile, and advanced technology.


Leave Your Message