The microlens array functions as the critical optical splitter that transforms a single raw laser beam into a precise matrix of 169 individual microbeams. This component is the enabling technology that allows the equipment to generate high-density fractional microchannels across the skin in a single pass.
The microlens array solves the conflict between permeability and safety. By splitting the beam, it creates a large effective area for drug delivery while preserving "bridges" of healthy tissue to accelerate healing.
Precision Beam Fractionation
The primary mechanical function of the microlens array is to alter the geometry of the laser energy.
Creating the Microbeam Matrix
Without this array, the laser would deliver a single, solid spot of energy. The lens splits this input into 169 distinct microbeams.
Defining Channel Geometry
This splitting process is highly controlled. It results in microchannels that are approximately 100 μm in diameter.
Efficiency in Application
Because the array generates these beams simultaneously, the system can create high-density patterns in a single pass. This eliminates the need for repeated scanning or multiple pulses over the same area.
The Clinical Advantage of Fractional Design
The physical splitting of the beam directly translates to improved clinical outcomes for the patient.
Preserving Healthy Tissue
The array does not ablate the entire skin surface. Instead, it ensures that distinct areas of undamaged healthy tissue remain between the microchannels.
Accelerating Recovery
These bridges of healthy tissue are vital for the healing process. They serve as a reservoir of cells that migrate into the channels, significantly shortening the skin recovery period.
Reducing Complications
By limiting the trauma to specific micro-channels rather than a broad open wound, the array significantly reduces the risk of infection post-procedure.
Understanding the Trade-offs
While the microlens array offers significant advantages, it operates on the principle of "fractional" treatment, which implies specific limitations compared to full-surface ablation.
Coverage vs. Integrity
The array is designed to leave a specific percentage of skin untreated. While this improves safety, it means the total surface area available for drug absorption is physically limited by the space required for healthy tissue bridges.
Fixed Pattern Limitations
The array produces a fixed pattern (169 beams). This offers consistency and speed, but it lacks the flexibility to dynamically alter the density of the channels without changing the optical component or the overlap technique.
Making the Right Choice for Your Goal
The microlens array is a tool for balancing efficacy with patient safety.
- If your primary focus is Drug Delivery Efficiency: Rely on the high-density configuration (169 beams per pass) to create the maximum number of pathways for absorption.
- If your primary focus is Patient Safety: Leverage the fractional design to ensure rapid closure of the 100 μm channels, minimizing downtime and infection risks.
The microlens array ultimately transforms a destructive laser beam into a precision tool for safe, permeable tissue modification.
Summary Table:
| Feature | Function of Microlens Array | Clinical Benefit |
|---|---|---|
| Beam Fractionation | Splits 1 beam into 169 microbeams | High-density channel creation in one pass |
| Channel Diameter | Precision control at ~100 μm | Minimally invasive micro-trauma |
| Tissue Preservation | Maintains healthy tissue "bridges" | Accelerated recovery and cell migration |
| Pattern Design | Fixed high-density matrix | Consistent drug delivery pathways |
| Safety Profile | Limits total ablation area | Reduced risk of infection and downtime |
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References
- Elina A. Genina, Valery V. Tuchin. Transcutaneous delivery of micro- and nanoparticles with laser microporation. DOI: 10.1117/1.jbo.18.11.111406
This article is also based on technical information from Belislaser Knowledge Base .
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