Knowledge What are the indications for using a picosecond laser? Professional Guide to Tattoo and Pigment Clearance
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Tech Team · Belislaser

Updated 2 days ago

What are the indications for using a picosecond laser? Professional Guide to Tattoo and Pigment Clearance


The primary indication for a picosecond laser is tattoo removal, specifically for clearing difficult pigments like blue and green or treating tattoos that have proven resistant to traditional Q-switched lasers. Beyond tattoos, this technology is widely indicated for treating benign pigmented lesions, including melasma, Naevus of Ota, Naevus of Ito, solar lentigines, and minocycline-induced pigmentation. Furthermore, when equipped with a fractionated handpiece, the device is indicated for tissue remodeling to address acne scarring, photoaging, and rhytides (wrinkles).

Core Takeaway: Picosecond lasers utilize ultrashort pulses (trillionths of a second) to deliver high peak power that shatters pigment while minimizing heat damage to surrounding tissue. This makes them a superior choice for clearing stubborn pigmentation and tattoos with fewer treatments and reduced risk of side effects compared to older nanosecond technology.

1. Advanced Tattoo Removal

The most established role of the picosecond laser is the clearance of exogenous ink particles.

Targeting Resistant Pigments

Picosecond lasers are particularly effective at clearing blue and green pigments. These colors are historically difficult to eliminate using standard nanosecond Q-switched lasers.

Treating Refractory Tattoos

This technology is indicated for "clean-up" cases. It is often used to treat tattoos that have stopped fading (become refractory) after multiple sessions with older laser therapies.

Reduced Treatment Frequency

Due to the efficiency of the high peak power and short pulse duration, patients typically require fewer total treatments to achieve clearance compared to nanosecond devices.

2. Treatment of Pigmentary Disorders

Picosecond technology allows for the selective destruction of endogenous melanin without damaging healthy, normal tissue.

Benign Pigmented Lesions

The laser is indicated for a variety of epidermal and dermal pigment issues. This includes solar lentigines (sun spots/age spots) and birthmarks such as Naevus of Ota and Naevus of Ito.

Melasma Management

Picosecond lasers are reported as an effective treatment for melasma. Because the pulse is so short, it reduces the thermal retention in the skin, which is critical for managing melasma without triggering a flare-up.

Drug-Induced Pigmentation

The technology is also indicated for specific, difficult cases such as pigmentation induced by the antibiotic minocycline.

3. Skin Remodeling and Rejuvenation

While standard beams target color, specific configurations of the laser target texture.

The Necessity of Fractionated Handpieces

To use a picosecond laser for structural skin improvement, it must be equipped with a fractionated handpiece. This splits the beam to create microscopic zones of injury that stimulate healing.

Scarring and Wrinkles

With the fractionated optic, the laser is indicated for treating acne scarring. It also facilitates tissue remodeling to address signs of photoaging and rhytides (fine lines and wrinkles).

Understanding the Trade-offs

While picosecond lasers offer significant advantages, it is important to understand the operational context and potential limitations.

Hardware Dependency

Not all picosecond lasers can treat every condition equally. The specific medium used—Nd:YAG (532/1064 nm) or Alexandrite (755 nm)—determines the specific wavelengths available, which dictates which pigment colors can be targeted effectively.

Risk Reduction, Not Elimination

Picosecond lasers present a reduced risk of scarring and hypopigmentation (lightening of the skin) compared to nanosecond lasers. However, while "minimal collateral damage" is a key advantage, proper energy settings and patient selection remain critical to avoid side effects.

Requirement for Add-ons

As noted, treating texture issues like acne scars or wrinkles is not possible with the standard pigment-shattering beam alone. You must ensure the specific device includes the fractionated handpiece capability to treat these indications.

Making the Right Choice for Your Goal

  • If your primary focus is stubborn tattoo removal: Prioritize this laser for its ability to clear blue/green ink and finish tattoos that older lasers cannot remove.
  • If your primary focus is treating melasma: Select this technology for its ability to target pigment with minimal thermal damage, reducing the risk of worsening the condition.
  • If your primary focus is acne scarring or wrinkles: Ensure the specific device is equipped with a fractionated handpiece to enable tissue remodeling capabilities.

Picosecond lasers represent a shift from thermal-dominant treatments to stress-dominant treatments, offering a more precise tool for clearing pigment and remodeling skin with less downtime.

Summary Table:

Indication Category Specific Conditions Key Advantage
Tattoo Removal Blue/green ink, refractory/stubborn tattoos Shatters ink with fewer sessions
Pigmentary Disorders Melasma, Solar Lentigines, Naevus of Ota Minimal thermal damage, lower side effect risk
Skin Rejuvenation Acne scars, photoaging, rhytides (wrinkles) Stimulates remodeling via fractionated handpiece
Specific Lesions Drug-induced (minocycline) pigmentation Precise targeting of difficult dermal pigments

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