Knowledge What were the clinical and histologic outcomes of ELOS (RF+IPL) studies? Transform Skin with Data-Backed Results
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Tech Team · Belislaser

Updated 2 days ago

What were the clinical and histologic outcomes of ELOS (RF+IPL) studies? Transform Skin with Data-Backed Results


Studies evaluating ELOS systems that combine bipolar radiofrequency (RF) with intense pulsed light (IPL) demonstrate significant positive outcomes in both visible skin quality and underlying tissue structure. Clinically, patients experienced substantial improvements in skin tightening, texture, and wrinkle reduction, while histologic analysis confirmed these results through measurable increases in collagen density and epidermal thickness.

Research confirms that this dual-energy modality not only improves visible signs of aging by over 75% but also induces quantifiable biological changes, including a 28% increase in new collagen synthesis.

Clinical Performance and Patient Satisfaction

Measurable Improvements in Skin Quality

Data from a large-scale study involving 108 patients indicates a broad efficacy for this technology. Participants experienced a 75.3% overall skin improvement, a metric that aggregates positive changes in wrinkles, pore size, and pigmentation.

Impact on Laxity and Tightening

Beyond surface texture, the combination of RF and IPL effectively addresses structural firmness. The large-scale study reported a 62.9% improvement in skin laxity.

In a separate, smaller cohort of 6 subjects, results were even more pronounced at 3 months post-treatment. These subjects demonstrated 75% to 80% improvement in skin tightening.

Reductions in Wrinkles and Texture

The targeted application of ELOS systems appears particularly effective for fine lines. The smaller study noted a 95% to 100% improvement in wrinkles.

Texture outcomes were similarly high, with observed improvements ranging from 70% to 75%.

High Patient Satisfaction Rates

Subjective patient feedback aligns closely with clinical observation. In the larger study, 92% of patients reported satisfaction at the 15-week mark. The smaller cohort reported 95% to 100% overall satisfaction.

Histologic Evidence of Structural Change

Increases in Collagen Production

Histologic analysis provides the biological validation for the visible tightening described above. Tissue samples revealed a 28% increase in newly synthesized collagen fibers. This suggests the treatment successfully initiates the body's wound-healing response to rebuild structural support.

Changes in Elastin Content

The studies also quantified changes in elastin, a protein critical for skin snap and resilience. Analysis showed a 53% reduction in elastin content, indicating a remodeling of the dermal matrix.

Epidermal Thickening

The treatment stimulates the upper layers of the skin as well. Histology confirmed increased epidermal thickening, which contributes to a more robust skin barrier and smoother surface texture.

Understanding the Data Context

Variability in Sample Sizes

When evaluating these outcomes, it is critical to distinguish between the study cohorts. The most dramatic percentages (95-100% improvement) were derived from a very small group of only 6 subjects.

While the larger study of 108 patients still showed strong results, the percentages were more conservative (62.9% to 75.3%). This variance is typical in clinical research but suggests that individual results may vary.

Multifactorial Improvement Scores

The "overall skin improvement" metric combines several variables, including pigmentation and pore size. It is important to understand that ELOS systems are multi-application platforms. Success depends on treating the skin holistically rather than targeting a single isolated defect without considering the surrounding tissue condition.

Making the Right Choice for Your Goal

  • If your primary focus is structural tightening: The data supports this modality for laxity issues, evidenced by a 62.9% clinical improvement and confirmed by a 28% increase in collagen fibers.
  • If your primary focus is surface rejuvenation: You can expect high efficacy in treating wrinkles and texture, with patient satisfaction rates consistently exceeding 90%.

The combination of bipolar RF and IPL offers a scientifically validated method to simultaneously remodel the dermis and refine the epidermis for comprehensive skin rejuvenation.

Summary Table:

Metric Category Clinical Improvement (Avg) Histologic/Biological Change
Overall Skin Quality 75.3% Improvement Increased Epidermal Thickening
Skin Tightening & Laxity 62.9% - 80% Improvement 28% New Collagen Synthesis
Wrinkle Reduction 95% - 100% Improvement 53% Elastin Matrix Remodeling
Patient Satisfaction 92% - 100% Satisfaction Validated Wound-Healing Response

Elevate Your Clinic’s Results with BELIS Advanced Technology

Are you looking to provide your clients with the clinically proven results of combined energy modalities? BELIS specializes in professional-grade medical aesthetic equipment designed exclusively for clinics and premium salons.

Our extensive portfolio features advanced laser systems (Diode, CO2 Fractional, Nd:YAG, Pico), HIFU, and Microneedle RF, alongside specialized body sculpting solutions like EMSlim and Cryolipolysis. Whether you need high-precision skin testers or powerful rejuvenation platforms, BELIS delivers the reliability and innovation your business deserves.

Ready to upgrade your services? Contact BELIS today to find the perfect system for your practice!

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